A “normal” level of hemoglobin is usually in the range of 14-17gm/dL for men, and 12-15gm/dL for women. However, different laboratories may define the normal range slightly differently. A low hemoglobin level — meaning, it’s below normal — can be used to detect anemia. Is hemoglobin 10.5 normal? According toRead More →
A low hemoglobin count is generally defined as less than 13.5 grams of hemoglobin per deciliter (135 grams per liter) of blood for men and less than 12 grams per deciliter (120 grams per liter) for women. What is the reason for low hemoglobin? In general, low hemoglobin levels thatRead More →
Red blood cells produce a protein called hemoglobin, which helps them carry out their primary function—transporting oxygen from the lungs to the body’s tissues. Hemoglobin is the protein that makes it possible for red blood cells to carry oxygen. Each molecule of hemoglobin is made up of four protein chains.Read More →
The recent development of automated systems for hematology analysis has made it possible to measure reticulocyte hemoglobin equivalent (RET-He), which is thought to reflect iron content in reticulocytes, in the same sample used for complete blood count tests. What is reticulum composed of in reticulocyte? The rate of reticulocyte releaseRead More →
The most common cause of congenital methemoglobinemia is cytochrome b5 reductase deficiency (type Ib5R). This enzymatic deficiency is endemic in certain Native American tribes (Navajo and Athabaskan Alaskans). Most cases of methemoglobinemia are acquired and result from exposure to certain drugs or toxins. What happens with too much nitrates? YouRead More →
A high RBC count may be a result of sleep apnea, pulmonary fibrosis, and other conditions that cause low oxygen levels in the blood. Performance-enhancing drugs like protein injections and anabolic steroids can also increase RBCs. Kidney disease and kidney cancers can lead to high RBC counts as well. CanRead More →
The 6 major and 2 short α-helices that make up the structure of a Hb subunit (the “globin fold”) are labeled A through H, which is the traditional naming scheme. Does hemoglobin have helical regions? THE STRUCTURE OF HEMOGLOBIN The ‘globin fold’ characteristic of Mb and Hb is built byRead More →